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High-Sensitivity Single-Cell Sample Introduction System

High-Sensitivity Single-Cell Sample Introduction System
Single-Cell Components
  • Make up Gas Inlet
  • MicroJet Adapter
  • Spray Chamber
  • Drain
  • Nebulizer Gas Inlet
  • High efficiency Single-Cell Nebulizer

Conventional ICP-MS spray chambers have low transport efficiencies (typically < 5% TE) that filter out larger droplets ( > 5um) from the nebulizer aerosol. As most cell lines of interest are larger than 5um, the secondary filtering mechanism of conventional spray chamber designs rejects a high proportion of the cells from passing to the plasma. To overcome this significant deficiency the Glass Expansion spray chamber design for single cell analysis is different from conventional ICP-MS spray chambers.

The low volume on-axis spray chamber with the patent pending MicroJet Adaptor simultaneously provide

  • On-axis, laminar high transmission efficiency spray chamber.
  • Excellent washout between samples.
  • High velocity sheathing gas entraining and shaping the nebulizer aerosol plume to prevent cell deposition on the spray chamber walls.

Glass Expansion's single cell nebulizer with proprietary VitriCone sample channel features

  • Superb transport efficiency at low sample uptake rates (15 to 45 uL/min)
  • Constant diameter, large bore sample channel minimizes blockages from sample build-up
  • Rigid, precision machined thick-walled glass sample capillary gives the best analytical precision
  • Inert, metal-free DC gas fittings with ratchet mechanism give reliable, reproducible leak-free Ar connections
  • Easy to use, gas tight, zero dead volume sample fittings make connecting to the sample delivery system easy and reliable

Single-Cell Sample Introduction System Ordering Information

AW Part Number OEM Part Number Description
KT-1155 - - - - - Single-Cell Sample Introduction System for Agilent ICP-MS
KT-1172 - - - - - Single-Cell Sample Introduction System for Thermo ICP-MS and TOFWERK icpTOF
KT-1184 - - - - - Single-Cell Sample Introduction System for PerkinElmer NexION 1000/2000 ICP-MS
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